Quantum dots are an established class of nanomaterials prominent in imaging and therapy due to their ability to interact with light. Recent research has also demonstrated their potential to form radicals by generating an electron-hole pair upon excitation with a light source.¹ Generated radicals can be utilized to initiate free-radical polymerization where the quantum dots act as photoinitiators. In this study, we explore anionic silver indium sulfide (AgInSâ‚‚) quantum dots² as long-wavelength photoinitiators in aqueous media. We report, for the first time, the use of AgInSâ‚‚ quantum dots to initiate polymerization under various irradiation wavelengths, most significantly the near-infrared region. The nanoparticles remain intact within the produced gels, and preserve their luminescence. This system presents an environmentally friendly alternative to common photoinitators due to water solubility and low energy consumption. Moreover, its two-component simplicity and low equipment cost make it easily scalable while increased curing depth makes it a suitable candidate for industrial applications.