Silicone elastomers such as poly(dimethylsiloxane) (PDMS) have received great attention regarding their potential use as anti-bioadhesion coatings1. It is widely used to reduce or prevent bioadhesion in biomedical and marine fields. The main properties responsible for its efficiency are low surface tension, low roughness and a Young’s modulus of a few MPa2. To date, only a few studies have looked at the relationship between the network structure, the coatings properties and the anti-bioadhesion efficiency. Our previous work has shown the influence of PDMS molecular weight on antibioadhesive properties coatings with no variation in surface properties3 with molecular weights ranging from 800 g.mol-1 and 10 000 g.mol-1. PDMS were modified to have trimethoxysilane end-groups and coatings were prepared by condensation reaction. Ellipsometry analysis in hexane and AFM measurements were carried out to evaluate the network structure. In addition, the chemical and mechanical surface properties were evaluated by contact angle and nanoindentation measurements.